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    Neuroscience

    Pictured above: Part of the graphical abstract of the article, "Functional thalamocortical connectivity development and alterations in preterm infants during the neonatal period," highlighted below. 

    Established in 1976, Neuroscience is the flagship journal of IBRO and is overseen by the IBRO Publications CommitteeElsevier publishes 28 issues per year. 

    The journal features papers describing the results of original research on any aspect of the scientific study of the nervous system. Any paper, however short, is considered for publication provided that it reports significant, new and carefully confirmed findings with full experimental details.

    READ THE CURRENT ISSUE OF IBRO Neuroscience (vol. 356) published on 25 July 2017.

    Highlights from this issue include:

    Audiovisual speech integration in the superior temporal region is dysfunctional in dyslexia

    (Zheng Ye, Jascha Rüsseler, Ivonne Gerth, Thomas F. Münte)

    Dyslexia is an impairment of reading and spelling that affects both children and adults even after many years of schooling. Dyslexic readers have deficits in the integration of auditory and visual inputs but the neural mechanisms of the deficits are still unclear. This fMRI study examined the neural processing of auditorily presented German numbers 0–9 and videos of lip movements of a German native speaker voicing numbers 0–9 in unimodal (auditory or visual) and bimodal (always congruent) conditions in dyslexic readers and their matched fluent readers. Results suggested that superior temporal dysfunction may underly poor audiovisual speech integration in readers with dyslexia.

    Functional thalamocortical connectivity development and alterations in preterm infants during the neonatal period

    (Yue Cai, Xiushuang Wu, Zihui Su, Yuan Shi, Jia-Hong Gao)

    The thalamus is one of the most commonly affected brain regions in preterm infants, particularly in infants with white matter lesions (WML). The aim of this paper is to explore the development and alterations of the functional thalamocortical connectivity in preterm infants with and without punctate white matter lesions (PWMLs) during the period before term equivalent age (TEA). Our results reveal that compared with normal preterm (NP) infants, PWML infants exhibit slightly altered thalamo-SA connectivity, and this alteration is deduced to be functional compensations for inefficient thalamocortical processing due to PWMLs.

    Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model

    (L.M. Dati, H. Ulrich, C.C. Real, Z.P. Feng, H.S. Sun, L.R. Britto)

    Carvacrol is a monoterpene that has been linked to neuroprotection in several animal models of neurodegeneration, including ischemia, epilepsy and traumatic neuronal injury. In this study, we investigated the effects of carvacrol (i.p.) upon the neurodegeneration induced by 6-hydroxy-dopamine unilateral intrastriatal injections in mice. Results suggest that carvacrol promotes a marked neuroprotection in the 6-hydroxy-dopamine model of Parkinson’s disease, possibly by its non-specific blocking effect upon TRPM7 channels.

     

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