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    Pictured above: Figure 1 of the article "Investigation of the effects of transcranial alternating current stimulation (tACS) on self-paced rhythmic movements" highlighted below. 

    Established in 1976, Neuroscience is the flagship journal of IBRO and is overseen by the IBRO Publications CommitteeElsevier publishes 28 issues per year. 

    The journal features papers describing the results of original research on any aspect of the scientific study of the nervous system. Any paper, however short, is considered for publication provided that it reports significant, new and carefully confirmed findings with full experimental details.

    READ THE CURRENT ISSUE OF IBRO Neuroscience (vol. 350)  published on 14 May 2017.

    Highlights from this issue include:

    Interlimb differences in coordination of unsupported reaching movements

    (Jacob E. Schaffera, Robert L. Sainburg)

    The current study explores interlimb differences in control of 3-D unsupported reaching movements. While the task was presented in the horizontal plane, participant’s arms were unsupported and free to move within a range of the vertical axis, which was redundant to the task plane. Results indicated significant dominant arm advantages for both initial direction accuracy and final position accuracy. The dominant arm controller was able to take advantage of the redundant degrees of freedom of the task, while non-dominant task errors appeared enslaved to motion along the redundant axis. 

    Investigation of the effects of transcranial alternating current stimulation (tACS) on self-paced rhythmic movements

    (Manuel Varlet, Alanna Wade, Giacomo Novembre, Peter E. Keller)

    Here we investigate whether entrainment of self-paced rhythmic movements can be induced via transcranial alternating current stimulation (tACS), which uses alternating currents to entrain spontaneous brain oscillations at specific frequencies. The comparison of participants’ movement frequency, amplitude, variability, and phase synchrony with and without tACS failed to reveal entrainment or movement modifications across the two experiments. However, significant differences in stimulation-related side effects reported by participants were found between the two experiments. Although other stimulation protocols may be effective, our results suggest that rhythmic movements such as pendulum swinging or locomotion that are low in goal-directedness and/or strongly driven by peripheral and mechanical constraints may not be susceptible to modulation by tACS.

    Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits

    (Matheus Teixeira Rossignoli, Cleiton Lopes-Aguiar, Rafael Naime Ruggiero, Raquel Araujo Do Val da Silva, Lezio Soares Bueno-Junior, Ludmyla Kandratavicius, José Eduardo Peixoto-Santos, José Alexandre Crippa, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, Raphael Escorsim Szawka, Janete Anselmo-Franci, João Pereira Leite, Rodrigo Neves Romcy-Pereira)

    Evidence indicates that prefrontal cortex (PFC) engagement in aversive memory formation seems to be recruited at specific time windows after memory acquisition, which has implications for the treatment of post-traumatic stress disorders. Cannabidiol (CBD), the major non-psychotomimetic phytocannabinoid of the Cannabis sativa plant, is known to modulate contextual fear memory acquisition in rodents. It is still not clear how CBD interferes with PFC-dependent processes during post-training memory consolidation. Here, we tested whether intra-PFC infusions of CBD immediately after or 5 h following contextual fear conditioning was able to interfere with memory consolidation. Our findings support that CBD interferes with contextual fear memory consolidation by reducing PFC influence on cortico-limbic circuits. 

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